EE 40332/60332Introduction to Biophotonics (Spring)

Schedule: Search University schedule
Credit hours: 3
Course website: on Sakai


The goal of this course is to provide students with the knowledge to understand and apply state-of-the-art biomedical optical imaging and sensing techniques. This course will teach the fundamentals of light interactions with biological tissues, the preclinical and clinical applications of biomedical optical imaging/sensing, and the instrumentation required to do so. Topics explored include diffuse optics, tissue spectroscopy, fluorescence imaging, optical coherence tomography, confocal and nonlinear microscopy techniques, endoscopy, photoacoustics, and laser surgery.  

Course Objectives

Upon successful completion of this course, you will be able to:

  • Describe the interaction of light with cells and tissues, the function and purpose of passive and optical elements used in biophotonics imaging/sensing techniques, and the most common optical imaging/sensing techniques used in biomedical applications 
  • Analyze a biomedical imaging/sensing application and choose and defend the most appropriate biophotonics method/technique 
  • Evaluate and criticize state-of-the-art technical reports of biophotonics imaging/sensing techniques and applications 
  • Create and evaluate a scientific/technical research proposals related to topics in biophotonics

Course Topics (may change based upon student interest)

  • Nature of light
  • Fundamentals of optics
  • Light sources and detectors
  • Optical fibers
  • Fluorescence
  • Light scattering (single and multiple)
  • Diffuse optics
  • Microscopy
  • Optical coherence tomography (OCT)
  • Photoacoustic imaging
  • Flow imaging ( Laser speckle, Doppler, Diffuse correlation spectroscopy)
  • Optical biosensors
  • Optical tweezers
  • Laser treatment, photodynamic therapy